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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
13.33
Human Site:
S435
Identified Species:
22.56
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S435
P
K
K
Q
K
N
E
S
N
S
A
G
S
P
A
Chimpanzee
Pan troglodytes
XP_509445
540
59236
P274
E
S
N
S
A
G
S
P
P
T
W
S
L
T
S
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S435
P
K
K
Q
K
K
E
S
N
S
A
G
S
P
A
Dog
Lupus familis
XP_534658
709
78944
S435
P
K
K
Q
K
K
E
S
S
S
G
A
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S438
K
K
Q
R
K
E
G
S
A
A
A
S
P
A
D
Rat
Rattus norvegicus
NP_001099399
476
51796
P210
S
Q
S
S
P
N
S
P
K
K
Q
R
R
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
N432
P
K
K
Q
K
R
G
N
S
T
V
S
S
S
T
Chicken
Gallus gallus
Q5F3D1
613
68449
S347
I
D
S
D
V
E
V
S
Q
R
S
Q
T
T
N
Frog
Xenopus laevis
Q6DD45
743
82926
K420
S
S
E
R
K
R
Q
K
T
S
G
N
H
T
V
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
A419
G
S
D
Q
T
L
Q
A
S
D
M
E
I
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
S287
A
L
F
N
A
D
G
S
E
V
T
K
S
D
E
Honey Bee
Apis mellifera
XP_001122586
556
62911
Y290
E
E
G
D
R
D
Q
Y
D
I
K
K
I
Y
D
Nematode Worm
Caenorhab. elegans
P34656
453
51815
R187
D
I
P
E
H
I
Y
R
M
R
R
L
G
L
I
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
K360
A
V
D
E
D
A
E
K
I
T
P
H
S
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
0
93.3
73.3
N.A.
26.6
6.6
N.A.
40
6.6
13.3
6.6
N.A.
13.3
0
0
13.3
P-Site Similarity:
100
13.3
93.3
80
N.A.
46.6
13.3
N.A.
60
20
33.3
33.3
N.A.
20
33.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
15
8
0
8
8
8
22
8
0
8
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
15
15
8
15
0
0
8
8
0
0
0
8
15
% D
% Glu:
15
8
8
15
0
15
29
0
8
0
0
8
0
15
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
8
22
0
0
0
15
15
8
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
8
8
0
0
0
8
0
0
8
8
0
0
15
0
8
% I
% Lys:
8
36
29
0
43
15
0
15
8
8
8
15
0
8
0
% K
% Leu:
0
8
0
0
0
8
0
0
0
0
0
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
8
8
0
15
0
8
15
0
0
8
0
0
8
% N
% Pro:
29
0
8
0
8
0
0
15
8
0
8
0
8
22
0
% P
% Gln:
0
8
8
36
0
0
22
0
8
0
8
8
0
0
0
% Q
% Arg:
0
0
0
15
8
15
0
8
0
15
8
8
8
0
8
% R
% Ser:
15
22
15
15
0
0
15
43
22
29
8
22
43
8
15
% S
% Thr:
0
0
0
0
8
0
0
0
8
22
8
0
8
22
8
% T
% Val:
0
8
0
0
8
0
8
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _